RESEARCH ON VALUES OF SERUM ACTIVIN-A CONCENTRATION IN DIAGNOSIS OF ECTOPIC PREGNANCY
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SUMMARY
Objectives: To determine values of serum Activin-A and β-hCG concentrations in diagnosis
of ectopic pregnancy (EP). Subjects and methods: A cross-sectional study conducted on
351 cases who were followed EP at the National Hospital for Obstetric and Gynaecolocy,
and Military Hospital 103 from 9/2017 - 11/2019. Results: There were 194 cases of EP and
157 cases of intrauterine pregnancy (IUP). Mean serum concentration of Activin-A, β-hCG in EP
group (2,440.9 pg/mL; 3,161.5 mUI/mL) was lower compared to IUP group (11,770.8 pg/mL,
39,185.8 mUI/mL); the difference was statistically significant (p < 0.05). The cut-off threshold
of Activin-A was 3,233.7 pg/mL; β-hCG was 4921.5 mUI/mL; differential diagnosis of Activin-A
and β-hCG between EP and IUP group had sensitivity of 87.1% and 91.7%, respectively;
specificity of 27.3% and 71.3%, respectively; the difference was statistically significant (p < 0.05).
Conclusion: Concentration of serum Activin-A and β-hCG levels were significant in the differential
diagnosis of EP and IUP.
Mô tả
* Keywords: Activin-A; Ectopic pregnancy; Intrauterine pregnancy.
Năm xuất bản
2020
Tác giả
Dao Nguyen, Hung
Đỗ Minh, Trung
Vũ Tùng, Sơn
Nhà xuất bản
Journal of military pharmaco-medicine
